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Writer's pictureJanna Mustafina, MSN, FNP-BC

Lets talk about Phentermine...

Updated: Feb 4, 2022

Phentermine (Adipex-P), is the most prescribed weight loss medication. Available as a low cost generic, Phentermine has been approved for weight loss since 1973.







How does phentermine work? Phentermine increases release of neurotransmitters which simulate metabolism and suppress appetite. Phentermine is a “sympathomimetic” because it simulates the release and inhibition of certain neurotransmitters in your brain. Essentially it tricks your mind into feeling full.


Release of which neurotransmitters? There are three neurotransmitters: dopamine, serotonin, and norepinephrine in the brain elevation of which results in hunger suppression.

What is the difference between phentermine, cocaine, and amphetamines? Cocaine and methamphetamines are much more potent releasers of norepinephrine and dopamine, which cause users to experience the addictive effects.


Who should not take phentermine? Phentermine should not be used in patients with coronary heart disease, uncontrolled high blood pressure, uncontrolled hyperthyroidism, or in patients with history of drug abuse.


Why is phentermine a “scheduled” drug like Xanax, Ativan or Ambien? Phentermine is a schedule IV drug, which suggests the potential for abuse. The potential for abuse is very low. If you are concerned, talk to your doctor about the potential for addictive effects.


How much weight will I loose with phentermine? Phentermine 37.5mg daily for 12 weeks leads to an average weight loss of 15.8 lbs.


What are the side effects? The most common side effects are dry mouth and constipation. Phentermine can also cause an increased heart rate, elevated blood pressure, insomnia, constipation, and nervousness. Keep an eye on your blood pressure if you do decide to lose weight with Phentermine.


I want to get a prescription for Phentermine. At eCareNow we offer medical weight loss services and you can get a prescription for Phentermine if appropriate and safe for your health condition. Our provider will then coach and monitor your progress via telemedicine visits. If interested, book an appointment with us under Medical Weight Loss.


How much does Phentermine cost? The cost varies in different pharmacies. We usually advise patients to use WalMart, Costco, Giant pharmacies where you can purchase 30 tab of Phentermine for a very low price (between $10.00 - $18.00)



Have you lost weight on Phentermine? Please share your experience...

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